Do not administer the drug to the following patients: Patients with hypersensitivity to its components; patients with complete obstruction of biliary tract (choleretic actions may aggravate the symptoms); patients with fulminant hepatitis; patients with radiopaque calcifying cholelithiasis; patients with nonfunctioning gall bladder or acute cholecystitis; pregnant women or women suspected of being pregnant; pediatric patients; patients with renal disease; patients with gastric ulcers (acute gastroduodenal ulcers); patients with colitis or enteritis such as Crohn's disease.